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What Is Morphine?

Morphine, (avinza) is a pain medication of the opiate family which is found naturally in a number of plants and animals. It acts directly on the central nervous system to decrease the feeling of pain.

Morphine is a naturally occurring substance extracted from either the opium poppy plant or concentrated poppy straw. Its chemical makeup is similar to heroin, as they are both extracted from the same plant.

Mostly used as a medication for severe pain, Morphine belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain.

Named after Morpheus, the Greek god of dreams, morphine provides a feeling of euphoria oft-described as a dreamlike state. The drug can be taken in the form of a tablet, syrup, or injection. In some cases, morphine can even be smoked.

Short-acting formulations are taken as needed for pain. Morphine extended-release pills are for around-the-clock treatment of pain. This form of morphine is not for use on an as-needed basis for pain. Morphine can be taken for both acute pain and chronic pain. It is frequently used for pain from myocardial infarction and during labor.

Important Facts About Morphine (Avinza).

Morphine pills were first isolated between 1803 and 1805 by Friedrich Sertürner. This is generally believed to be the first isolation of an active ingredient from a plant. Merck began marketing it commercially in 1827.
Morphine was more widely used after the invention of the hypodermic syringe in 1853–1855. Sertürner originally named the substance morphium after the Greek god of dreams, Morpheus, as it has a tendency to cause sleep.

Morphine has the potential to be highly addictive, as tolerance to it develops rapidly. A federally designated Schedule II drug. It is also used for pain relief after major surgeries, treatment for cancer-related pain, and shortness of breath at the end of a patient’s life.

Moreover, Avinza also has a high abuse potential because of its pleasurable effects and relative accessibility. Recently, Avinza pills have added abuse-deterrent coding so that they cannot be crushed, snorted, or injected. This has greatly reduced the addictive potential of prescribed Avinza pills.

Avinza pills can slow or stop your breathing and may be habit-forming, so you should not take morphine if you have severe asthma or breathing problems, a blockage in your stomach or intestines, or a bowel obstruction called paralytic ileus.

NB: The common street or slang names for morphine include M, Miss Emma, monkey, roxanol and white stuff.

How Do People Use Morphine Pills?

Morphine Pills can be given by mouth, by injection into a muscle, by injection under the skin, intravenously, injection into the space around the spinal cord, or rectally.

The maximum effect is reached after about 20 minutes when given intravenously and after 60 minutes when given by mouth, while the duration of effect is 3–7 hours. Long-acting formulations also exist.

Preservative-free morphine may also be given by a doctor as an injection into the area around the spinal cord or into the fluid-filled space that contains the spinal cord. In this case, the medication is first given in the hospital where you can be monitored closely.

If your doctor directs you to continue using this medication at home, it is usually given as a continuous injection using an infusion pump placed under your skin. The dosage is based on your medical condition and response to treatment. For children, the dosage may also be based on weight.

NB: Do not increase your dose, do not use the medication more frequently, do not use it for a longer time than prescribed. Properly stop the medication when so directed.

What Are The Side Effects Of Morphine?

Morphine side effects include respiratory depression and HypotensionMorphine is addictive and prone to abuse. If the dose is reduced after long-term use, opioid withdrawal symptoms may occur.

Common side effects include drowsiness, vomiting, and constipation. Caution is advised when used during pregnancy or breastfeeding, as morphine may affect the baby.

NB: Morphine use may also cause constipation or affect hormone imbalance in the following ways.


Morphine acts on the myenteric plexus in the intestinal tract, reducing gut motility, causing constipation. The gastrointestinal effects of this “MorphaBond ER” medication are mediated primarily by μ-opioid receptors in the bowel.

By inhibiting gastric emptying and reducing propulsive peristalsis of the intestine, morphine decreases the rate of intestinal transit. Reduction in gut secretion and increased intestinal fluid absorption also contribute to the constipating effect. 

Hormone imbalance:

This medication causes hypogonadism and hormone imbalances in chronic users of both sexes. This side effect is dose-dependent and occurs in both therapeutic and recreational users. This opioid medication can interfere with menstruation in women by suppressing levels of luteinizing hormone.

Many studies suggest the majority of chronic opioid users have opioid-induced hypogonadism. As of 2013, the effect of low-dose or acute use of morphine on the endocrine system is unclear

Important Warning Regarding Avinza Pills Use.

Morphine may cause serious or life-threatening breathing problems, especially during the first 24 to 72 hours of your treatment and any time your dose is increased. Your doctor will monitor you carefully during your treatment.

Inform your doctor if you have slow breathing or asthma. Your doctor may tell you not to take morphine. Also tell your doctor if you have or have ever had lung diseases such as chronic obstructive pulmonary disease a head injury, or any condition that increases the amount of pressure in your brain.

Drinking alcohol, taking prescription or nonprescription medications that contain alcohol, or using other street drugs during your treatment with morphine increases the risk that you might experience serious life-threatening side effects.

If you are taking Avinza brand long-acting capsules, it is especially important that you do not drink any drinks that contain alcohol or take any prescription or nonprescription medications that contain alcohol.

Alcohol may cause the morphine in Avinza pills long-acting capsules to be released in your body too quickly, causing serious health problems or death.

Do not allow anyone else to take your medication. This medication may harm or cause death to other people who take your medication, especially children. Keep this medication in a safe place so that no one else can take it accidentally or on purpose.

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